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After her astrophysicist father (Chris Pine) goes missing 13-year-old Meg (Storm Reid) meets three supernatural beings named Mrs. Whatsit (Reese Witherspoon) Mrs. Who (Mindy Kaling) and Mrs. Which (Oprah Winfrey). They transport her her friend Calvin (Levi Miller) and her brother Charles Wallace (Deric McCabe) through the universe where they must traverse strange new planets and unlock the power inside themselves to rescue her dad. Based on Madeleine L Engle s novel of the same name the first in a five-book series. Directed by Ava DuVernay. Gugu Mbatha-Raw Zach Galifianakis Bellamy Young and Michael Pe?a co-star.~Kaitlin Elise Miller.