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On an island in the Great Massasauga Swamp—an area known as “The Waters” to the residents of nearby Whiteheart, Michigan—herbalist Hermine “Herself” Zook has healed the local women of their ailments for generations. As stubborn as her tonics are powerful, Herself inspires reverence and fear in the people of Whiteheart, and even in her own three daughters. The youngest, beautiful and inscrutable Rose Thorn, has left her own daughter, eleven-year-old Dorothy “Donkey” Zook, to grow up wild. Donkey spends her days searching for truths in the lush landscape and in her math books, waiting for her wayward mother and longing for a father, unaware that family secrets, passionate love, and violent men will flood through the swamp and upend her idyllic childhood.